BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of affinity data for UniProtKB/TrEMBL: Q96QK1   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vacuolar protein sorting-associated protein 35


(Homo sapiens)		BDBM50253251
PNG
(CHEMBL4072637)
Show SMILES CNC(=O)c1nc(-c2nc(-c3cnc4ccccn34)c(C)nc2N)n(C)n1
Show InChI InChI=1S/C17H17N9O/c1-9-12(10-8-20-11-6-4-5-7-26(10)11)22-13(14(18)21-9)16-23-15(17(27)19-2)24-25(16)3/h4-8H,1-3H3,(H2,18,21)(H,19,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



IMED Oncology, AstraZeneca, Darwin Building, Cambridge Science Park, 319 Milton Road, Cambridge CB4 0WG, United Kingdom. Electronic address: bernard.barlaam2@astrazeneca.com.

Curated by ChEMBL


Assay Description
Inhibition of VPS35 (unknown origin)

Bioorg Med Chem Lett 27: 3030-3035 (2017)


Article DOI: 10.1016/j.bmcl.2017.05.028
BindingDB Entry DOI: 10.7270/Q23R0W9X
More data for this
Ligand-Target Pair